염증성 사이토카인과 구강 편평세포암종
Inflammatory Cytokines and Oral Squamous Cell Carcinoma
김도경, 배정윤, 박영진, 손화경, 이재훈, 김진,
소속 상세정보
김도경 ( Kim Do-Kyeong ) - 연세대학교 치과대학 구강병리학교실
배정윤 ( Bae Jung-Yoon ) - 연세대학교 치과대학 구강병리학교실
박영진 ( Park Young-Jin ) - 연세대학교 치과대학 구강병리학교실
손화경 ( Son Hwa-Kyung ) - 백석대학교 치위생학과
이재훈 ( Lee Jae-Hoon ) - 연세대학교 치과대학 보철과학교실
김진 ( Kim Jin ) - 연세대학교 치과대학 구강병리학교실
KMID : 0829220130370040133
Abstract
Inflammation functions as a double-edged sword against external stimulus. For instance, inflammation can have anti-cancer effect and simultaneously can play cancer-promoting factors. Recent studies have shown that cytokine plays an important role in tumor biology by influencing tumor growth, invasion and metastasis. We classify these cytokines by cancer type and review current knowledge of cytokines in terms of carcinogenesis. Here, we also focus on whether cytokines can act as biomarkers for early detection of oral squamous cell carcinoma (OSCC). This review will provide basis for further approach to study the role of cytokines in carcinogenesis and evaluating the possibilities of cytokines as biomarkers for cancer detection.
키워드
Cytokines; Biomarkers; Inflammation; Oral squamous cell carcinoma
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